Led by science, not hype

  • Rigorous R&D platform

    End-to-end product development run by our in-house team of scientists.

  • Scientifically validated claims

    Quantified by our proprietary MolClock and Skin Age Modeling methods.

  • Ongoing clinical studies

    Conducted by independent, third-party research organizations.

  • Peer-reviewed publications

    The gold standard for scientific research and in skin care.

      • 9+

        years of research

      • 900+

        peptides screened

      • 22+

        patents & publications

      • 12,000+

        5-Star Reviews

        OS-01: the new standard in peptide technology

        Think of OS-01 as a reset button for your skin, helping clear away the senescent cells that cause wrinkles, hyperpigmentation, and crepiness. As the first peptide scientifically proven to reduce cellular senescence in the skin, OS-01 does what other peptides can’t.

        Scientifically proven,visible results.

        OS-01 works by switching off the senescent-or aging-cells that drive aging of your skin, transforming skin to behave like its younger self.

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        How OS-01 Works

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        Scientifically proven to:

        Support cellular repair

        Text with iconBoosts biomarkers associated with collagen and hyaluronic acid

        Improve barrier function and epidermal thickness

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        Instantly

        Hydrated and soothed skin.

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        Within 2 weeks

        Sustained hydration and smoothness,
        with improved skin barrier.

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        3 Within 8 weeks

        Stronger, more resilient skin with reduced
        sagging and flakiness.

        See your skin transform

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        6 visible signs of senescence

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          Lines and wrinkles

          Caused by a decline in collagen and elastin production.

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          Loss of elasticity

          Decreased elastin also contributes to lack of firmness.

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          Uneven skin tone

          Irregular melanin production leads to hyperpigmentation.

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          Rough texture

          Compromised skin cell renewal leaves a dry, uneven surface.

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          Loss of volume

          Linked to a decrease in hyaluronic acid, collagen, and elastin.

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          Thinning skin

          Slower cell turnover contributes to a weakened skin barrier.

          Explore our peer-reviewed research

          Image with textThe brains behind the breakthrough

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            FAQs

            What are peptides?

            Peptides are short chains of amino acids. They represent a broad class of molecules with many jobs, from forming the building blocks of larger proteins to acting as cellular messengers. Peptides found naturally in the body (called endogenous peptides), play a crucial role in tissue growth, hormone regulation, and other biological processes. Exogenous peptides, which can be injected, ingested or delivered topically like OS-01, can send out signals to skin cells to trigger collagen and hyaluronic acid production, aid in cellular repair, and help strengthen the skin barrier.

            How does OS-01 work?

            OS-01 reduces the accumulation of senescent cells. These cells release inflammatory chemicals that cause neighboring cells to become dysfunctional, kicking off a domino effect in skin and accelerating skin aging. By reducing this inflammatory response, OS-01 helps prevent the accumulation of senescent cells in skin, improving key skin aging biomarkers and keeping other skin cells healthy and thriving.

            Who is OneSkin for?

            OneSkin is for everyone. Whether you’re taking a preventative approach or want your skin’s health and appearance to reflect how you feel on the inside, our scientifically proven products work at the cellular level to keep your skin looking, feeling, and acting younger and healthier as you age.

            What skin concerns does OneSkin address?

            Through lab studies and clinical studies, our products have been shown to combat the visible and invisible signs of aging, from collagen loss and thinning skin to a compromised barrier function.

            How long does it take to see results?

            With daily use, you can expect to see visible results within 12 weeks, though some people see changes even sooner. This time frame allows OS-01 to work at the cellular level, improving the long-term health and appearance of your skin.